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The Kynurenine Pathway and Kynurenine 3-Monooxygenase Inhibitors

Under normal physiological conditions, the kynurenine pathway (KP) plays a critical role in generating cellular energy and catabolizing tryptophan. Under inflammatory conditions, however, there is an upregulation of the KP enzymes, particularly kynurenine 3-monooxygenase (KMO). KMO has garnered much...

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Detalles Bibliográficos
Autores principales:	Hughes, Tamera D., Güner, Osman F., Iradukunda, Emma Carine, Phillips, Robert S., Bowen, J. Phillip
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8747024/ https://www.ncbi.nlm.nih.gov/pubmed/35011505 http://dx.doi.org/10.3390/molecules27010273

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