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Folding and Unfolding of Exogenous G-Rich Oligonucleotides in Live Cells by Fluorescence Lifetime Imaging Microscopy of o-BMVC Fluorescent Probe

Guanine-rich oligonucleotides (GROs) can self-associate to form G-quadruplex (G4) structures that have been extensively studied in vitro. To translate the G4 study from in vitro to in live cells, here fluorescence lifetime imaging microscopy (FLIM) of an o-BMVC fluorescent probe is applied to detect...

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Detalles Bibliográficos
Autores principales: Tseng, Ting-Yuan, Wang, Chiung-Lin, Huang, Wei-Chun, Chang, Ta-Chau
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8747072/
https://www.ncbi.nlm.nih.gov/pubmed/35011378
http://dx.doi.org/10.3390/molecules27010140

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