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Applying Box–Behnken Design for Formulation and Optimization of PLGA-Coffee Nanoparticles and Detecting Enhanced Antioxidant and Anticancer Activities

In an attempt to prove biological activity enhancement upon particle size reduction to the nanoscale, coffee (Cf) was chosen to be formulated into poly(lactic-co-glycolic) acid (PLGA) nanoparticles (NPs) using the single emulsion-solvent evaporation (SE-SE) method via Box–Behnken Design (BBD) to stu...

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Detalles Bibliográficos
Autores principales: Sharaf, Nouran S., Shetta, Amro, Elhalawani, Jailan E., Mamdouh, Wael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8747114/
https://www.ncbi.nlm.nih.gov/pubmed/35012166
http://dx.doi.org/10.3390/polym14010144