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The MEK1/2-inhibitor ATR-002 efficiently blocks SARS-CoV-2 propagation and alleviates pro-inflammatory cytokine/chemokine responses

Coronavirus disease 2019 (COVID-19), the illness caused by a novel coronavirus now called severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has led to more than 260 million confirmed infections and 5 million deaths to date. While vaccination is a powerful tool to control pandemic spread,...

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Detalles Bibliográficos
Autores principales: Schreiber, André, Viemann, Dorothee, Schöning, Jennifer, Schloer, Sebastian, Mecate Zambrano, Angeles, Brunotte, Linda, Faist, Aileen, Schöfbänker, Michael, Hrincius, Eike, Hoffmann, Helen, Hoffmann, Markus, Pöhlmann, Stefan, Rescher, Ursula, Planz, Oliver, Ludwig, Stephan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8747446/
https://www.ncbi.nlm.nih.gov/pubmed/35013790
http://dx.doi.org/10.1007/s00018-021-04085-1