Comparison of Single and Repeated Dosing of Anti-Inflammatory Human Umbilical Cord Mesenchymal Stromal Cells in a Mouse Model of Polymicrobial Sepsis

SUMMARY: Mesenchymal stromal cells (MSCs) ameliorate pre-clinical sepsis and sepsis-associated acute kidney injury (SA-AKI) but clinical trials of single-dose MSCs have not indicated robust efficacy. This study investigated immunomodulatory effects of a novel MSC product (CD362-selected human umbili...

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Detalles Bibliográficos
Autores principales: Fazekas, Barbara, Alagesan, Senthilkumar, Watson, Luke, Ng, Olivia, Conroy, Callum M., Català, Cristina, Andres, Maria Velascode, Negi, Neema, Gerlach, Jared Q., Hynes, Sean O., Lozano, Francisco, Elliman, Stephen J., Griffin, Matthew D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8747454/
https://www.ncbi.nlm.nih.gov/pubmed/35013938
http://dx.doi.org/10.1007/s12015-021-10323-7

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