First-Line Anlotinib Combined with Stereotactic Body Radiation Therapy for an Octogenarian with Pulmonary Carcinosarcoma

Pulmonary carcinosarcoma (PC) is a rare and highly malignant type of non-small cell lung cancer (NSCLC) that is insensitive to radiotherapy and chemotherapy and has a poor prognosis. Here, we report a case of an 88-year-old patient with inoperable PC and a history of cerebral infarction who was trea...

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Autores principales: Liang, Long, Chen, Taiyu, Ren, Tao, Mao, Mian, Wang, Keli, Tang, Chunhan, Xiao, Juan, Jia, Hongyuan, Chen, Wenli, Wang, Qifeng, Li, Tao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2022
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8747690/
https://www.ncbi.nlm.nih.gov/pubmed/35023973
http://dx.doi.org/10.2147/CMAR.S344149
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author Liang, Long
Chen, Taiyu
Ren, Tao
Mao, Mian
Wang, Keli
Tang, Chunhan
Xiao, Juan
Jia, Hongyuan
Chen, Wenli
Wang, Qifeng
Li, Tao
author_facet Liang, Long
Chen, Taiyu
Ren, Tao
Mao, Mian
Wang, Keli
Tang, Chunhan
Xiao, Juan
Jia, Hongyuan
Chen, Wenli
Wang, Qifeng
Li, Tao
author_sort Liang, Long
collection PubMed
description Pulmonary carcinosarcoma (PC) is a rare and highly malignant type of non-small cell lung cancer (NSCLC) that is insensitive to radiotherapy and chemotherapy and has a poor prognosis. Here, we report a case of an 88-year-old patient with inoperable PC and a history of cerebral infarction who was treated with first-line anlotinib combined with stereotactic body radiation therapy (SBRT). The therapeutic response has sustained for 10 months. Our work suggests that SBRT combined with anlotinib may be a safe and effective treatment strategy for octogenarians with PC.
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spelling pubmed-87476902022-01-11 First-Line Anlotinib Combined with Stereotactic Body Radiation Therapy for an Octogenarian with Pulmonary Carcinosarcoma Liang, Long Chen, Taiyu Ren, Tao Mao, Mian Wang, Keli Tang, Chunhan Xiao, Juan Jia, Hongyuan Chen, Wenli Wang, Qifeng Li, Tao Cancer Manag Res Case Report Pulmonary carcinosarcoma (PC) is a rare and highly malignant type of non-small cell lung cancer (NSCLC) that is insensitive to radiotherapy and chemotherapy and has a poor prognosis. Here, we report a case of an 88-year-old patient with inoperable PC and a history of cerebral infarction who was treated with first-line anlotinib combined with stereotactic body radiation therapy (SBRT). The therapeutic response has sustained for 10 months. Our work suggests that SBRT combined with anlotinib may be a safe and effective treatment strategy for octogenarians with PC. Dove 2022-01-06 /pmc/articles/PMC8747690/ /pubmed/35023973 http://dx.doi.org/10.2147/CMAR.S344149 Text en © 2022 Liang et al. https://creativecommons.org/licenses/by-nc/3.0/This work is published and licensed by Dove Medical Press Limited. The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution – Non Commercial (unported, v3.0) License (http://creativecommons.org/licenses/by-nc/3.0/ (https://creativecommons.org/licenses/by-nc/3.0/) ). By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. For permission for commercial use of this work, please see paragraphs 4.2 and 5 of our Terms (https://www.dovepress.com/terms.php).
spellingShingle Case Report
Liang, Long
Chen, Taiyu
Ren, Tao
Mao, Mian
Wang, Keli
Tang, Chunhan
Xiao, Juan
Jia, Hongyuan
Chen, Wenli
Wang, Qifeng
Li, Tao
First-Line Anlotinib Combined with Stereotactic Body Radiation Therapy for an Octogenarian with Pulmonary Carcinosarcoma
title First-Line Anlotinib Combined with Stereotactic Body Radiation Therapy for an Octogenarian with Pulmonary Carcinosarcoma
title_full First-Line Anlotinib Combined with Stereotactic Body Radiation Therapy for an Octogenarian with Pulmonary Carcinosarcoma
title_fullStr First-Line Anlotinib Combined with Stereotactic Body Radiation Therapy for an Octogenarian with Pulmonary Carcinosarcoma
title_full_unstemmed First-Line Anlotinib Combined with Stereotactic Body Radiation Therapy for an Octogenarian with Pulmonary Carcinosarcoma
title_short First-Line Anlotinib Combined with Stereotactic Body Radiation Therapy for an Octogenarian with Pulmonary Carcinosarcoma
title_sort first-line anlotinib combined with stereotactic body radiation therapy for an octogenarian with pulmonary carcinosarcoma
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8747690/
https://www.ncbi.nlm.nih.gov/pubmed/35023973
http://dx.doi.org/10.2147/CMAR.S344149
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