Cargando…

Biologics in Psoriasis: Updated Perspectives on Long-Term Safety and Risk Management

Biologics targeting Th1/Th17 cytokines have revolutionised psoriasis treatment. In addition to treatment effectiveness, it is important to define and understand the long-term risks of biologic therapy in order to guide therapy selection and minimise these risks for patients where possible. This revi...

Descripción completa

Detalles Bibliográficos
Autores principales: Al-Janabi, A, Yiu, Z Z N
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8747772/
https://www.ncbi.nlm.nih.gov/pubmed/35024352
http://dx.doi.org/10.2147/PTT.S328575
Descripción
Sumario:Biologics targeting Th1/Th17 cytokines have revolutionised psoriasis treatment. In addition to treatment effectiveness, it is important to define and understand the long-term risks of biologic therapy in order to guide therapy selection and minimise these risks for patients where possible. This review article summarises available evidence from trial data, observational studies and pharmacovigilance registries to explore key long-term risks of biologic treatment, and how these risks might be managed in clinical practice.