p53 p.Pro72Arg (rs1042522) and Mouse Double Minute 2 (MDM2) Single-Nucleotide Polymorphism (SNP) 309 Variants and Their Interaction in Chronic Lymphocytic Leukemia(CLL): A Survey in CLL Patients from Western Iran

Background: Chronic lymphocytic leukemia (CLL) is the most common leukemia in adults. The MDM2 and p53 are interacting proteins that play crucial roles in cell biology. Genetic variations of p53 and MDM2 have been identified in many cancers including CLL; among which are SNP309 in the promoter of MD...

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Detalles Bibliográficos
Autores principales: Jalilian, Nazanin, Maleki, Yosra, Shakiba, Ebrahim, Aznab, Mozafar, Rahimi, Ziba, Salimi, Mehdi, Rhimi, Zohreh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Tehran University of Medical Sciences, Hematology-Oncology and Stem Cell Transplantation Research Center 2021
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8748241/
https://www.ncbi.nlm.nih.gov/pubmed/35082997
http://dx.doi.org/10.18502/ijhoscr.v15i3.6846

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