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Hsa_circ_0005576 promotes osimertinib resistance through the miR‐512‐5p/IGF1R axis in lung adenocarcinoma cells

Osimertinib is a third‐generation epidermal growth factor receptor tyrosine kinase inhibitor (EGFR‐TKI) for lung adenocarcinoma (LUAD) harboring activating mutations, but patients ultimately develop acquired resistance. Circular RNAs are involved in EGFR‐TKI resistance, while the role of hsa_circ_00...

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Detalles Bibliográficos
Autores principales: Liu, Suo, Jiang, Zhibin, Xiao, Peng, Li, Xiaozhi, Chen, Yinji, Tang, Hao, Chai, Yanfei, Liu, Yicai, Zhu, Zhao, Xie, Qianyi, He, Wei, Ma, Yuchao, Jin, Longyu, Feng, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8748248/
https://www.ncbi.nlm.nih.gov/pubmed/34706132
http://dx.doi.org/10.1111/cas.15177