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Clinicopathological significance of CD28 overexpression in adult T‐cell leukemia/lymphoma

CD28, one of the costimulatory molecules, has a pivotal role in T‐cell activation, and its expression is strictly regulated in normal T cells. Gain‐of‐function genetic alterations involving CD28 have been frequently observed in adult T‐cell leukemia/lymphoma (ATLL). These abnormalities, such as CD28...

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Detalles Bibliográficos
Autores principales: Sakamoto, Yuma, Ishida, Takashi, Masaki, Ayako, Takeshita, Morishige, Iwasaki, Hiromi, Yonekura, Kentaro, Tashiro, Yukie, Ito, Asahi, Kusumoto, Shigeru, Iida, Shinsuke, Utsunomiya, Atae, Ueda, Ryuzo, Inagaki, Hiroshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8748252/
https://www.ncbi.nlm.nih.gov/pubmed/34738707
http://dx.doi.org/10.1111/cas.15191