Cargando…
Randomized Crossover-Controlled Evaluation of Simultaneous Bilateral Transcutaneous Electrostimulation of the Posterior Tibial Nerve During Urodynamic Studies in Patients With Lower Urinary Tract Symptoms
PURPOSE: Transcutaneous tibial nerve stimulation (TTNS) has proven to be a valuable treatment option for various lower urinary tract conditions, such as overactive bladder syndrome and neurogenic detrusor overactivity. The aim of this study was to investigate acute changes in urodynamic parameters d...
Autores principales: | , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Korean Continence Society
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8748303/ https://www.ncbi.nlm.nih.gov/pubmed/33504123 http://dx.doi.org/10.5213/inj.2040408.204 |
_version_ | 1784630992919592960 |
---|---|
author | Girtner, Florian Fritsche, Hans-Martin Zeman, Florian Huber, Toni Haider, Maximilian Pickl, Christoph Burger, Maximilian Mayr, Roman |
author_facet | Girtner, Florian Fritsche, Hans-Martin Zeman, Florian Huber, Toni Haider, Maximilian Pickl, Christoph Burger, Maximilian Mayr, Roman |
author_sort | Girtner, Florian |
collection | PubMed |
description | PURPOSE: Transcutaneous tibial nerve stimulation (TTNS) has proven to be a valuable treatment option for various lower urinary tract conditions, such as overactive bladder syndrome and neurogenic detrusor overactivity. The aim of this study was to investigate acute changes in urodynamic parameters due to bilateral TTNS. METHODS: Fifty-one patients (18–87 years; 61% female) with various lower urinary tract symptoms were enrolled in this study. They were single-blinded and randomly assigned to receive simultaneous bilateral TTNS either during their first urodynamic examination, followed by a second round using a placebo stimulation technique, or vice versa. RESULTS: For subjects without signs of anatomical pathologies, the filling volume at the first desire to void (FDV) increased significantly by 54 mL (interquartile range [IQR], 26–81 mL; P<0.01) under the influence of TTNS compared to placebo. The maximum cystometric capacity increased by 41 mL (IQR, 10–65 mL; P=0.02). The median micturition volume of patients with pathological postvoid residual volumes (>100 mL) increased by 76 mL compared to patients without urinary retention (IQR, 6–166 mL; P=0.03). CONCLUSIONS: Compared to placebo, simultaneous bilateral TTNS showed significant improvements in bladder functioning, such as delayed FDV, increased maximum cystometric capacity, and reduced urinary retention. Patients with signs of anatomical pathologies did not seem to benefit from TTNS. Further studies need to be conducted to compare the effectiveness of bilateral versus unilateral TTNS. |
format | Online Article Text |
id | pubmed-8748303 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Korean Continence Society |
record_format | MEDLINE/PubMed |
spelling | pubmed-87483032022-01-18 Randomized Crossover-Controlled Evaluation of Simultaneous Bilateral Transcutaneous Electrostimulation of the Posterior Tibial Nerve During Urodynamic Studies in Patients With Lower Urinary Tract Symptoms Girtner, Florian Fritsche, Hans-Martin Zeman, Florian Huber, Toni Haider, Maximilian Pickl, Christoph Burger, Maximilian Mayr, Roman Int Neurourol J Original Article PURPOSE: Transcutaneous tibial nerve stimulation (TTNS) has proven to be a valuable treatment option for various lower urinary tract conditions, such as overactive bladder syndrome and neurogenic detrusor overactivity. The aim of this study was to investigate acute changes in urodynamic parameters due to bilateral TTNS. METHODS: Fifty-one patients (18–87 years; 61% female) with various lower urinary tract symptoms were enrolled in this study. They were single-blinded and randomly assigned to receive simultaneous bilateral TTNS either during their first urodynamic examination, followed by a second round using a placebo stimulation technique, or vice versa. RESULTS: For subjects without signs of anatomical pathologies, the filling volume at the first desire to void (FDV) increased significantly by 54 mL (interquartile range [IQR], 26–81 mL; P<0.01) under the influence of TTNS compared to placebo. The maximum cystometric capacity increased by 41 mL (IQR, 10–65 mL; P=0.02). The median micturition volume of patients with pathological postvoid residual volumes (>100 mL) increased by 76 mL compared to patients without urinary retention (IQR, 6–166 mL; P=0.03). CONCLUSIONS: Compared to placebo, simultaneous bilateral TTNS showed significant improvements in bladder functioning, such as delayed FDV, increased maximum cystometric capacity, and reduced urinary retention. Patients with signs of anatomical pathologies did not seem to benefit from TTNS. Further studies need to be conducted to compare the effectiveness of bilateral versus unilateral TTNS. Korean Continence Society 2021-12 2021-01-27 /pmc/articles/PMC8748303/ /pubmed/33504123 http://dx.doi.org/10.5213/inj.2040408.204 Text en Copyright © 2021 Korean Continence Society https://creativecommons.org/licenses/by-nc/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/ (https://creativecommons.org/licenses/by-nc/4.0/) ) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Original Article Girtner, Florian Fritsche, Hans-Martin Zeman, Florian Huber, Toni Haider, Maximilian Pickl, Christoph Burger, Maximilian Mayr, Roman Randomized Crossover-Controlled Evaluation of Simultaneous Bilateral Transcutaneous Electrostimulation of the Posterior Tibial Nerve During Urodynamic Studies in Patients With Lower Urinary Tract Symptoms |
title | Randomized Crossover-Controlled Evaluation of Simultaneous Bilateral Transcutaneous Electrostimulation of the Posterior Tibial Nerve During Urodynamic Studies in Patients With Lower Urinary Tract Symptoms |
title_full | Randomized Crossover-Controlled Evaluation of Simultaneous Bilateral Transcutaneous Electrostimulation of the Posterior Tibial Nerve During Urodynamic Studies in Patients With Lower Urinary Tract Symptoms |
title_fullStr | Randomized Crossover-Controlled Evaluation of Simultaneous Bilateral Transcutaneous Electrostimulation of the Posterior Tibial Nerve During Urodynamic Studies in Patients With Lower Urinary Tract Symptoms |
title_full_unstemmed | Randomized Crossover-Controlled Evaluation of Simultaneous Bilateral Transcutaneous Electrostimulation of the Posterior Tibial Nerve During Urodynamic Studies in Patients With Lower Urinary Tract Symptoms |
title_short | Randomized Crossover-Controlled Evaluation of Simultaneous Bilateral Transcutaneous Electrostimulation of the Posterior Tibial Nerve During Urodynamic Studies in Patients With Lower Urinary Tract Symptoms |
title_sort | randomized crossover-controlled evaluation of simultaneous bilateral transcutaneous electrostimulation of the posterior tibial nerve during urodynamic studies in patients with lower urinary tract symptoms |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8748303/ https://www.ncbi.nlm.nih.gov/pubmed/33504123 http://dx.doi.org/10.5213/inj.2040408.204 |
work_keys_str_mv | AT girtnerflorian randomizedcrossovercontrolledevaluationofsimultaneousbilateraltranscutaneouselectrostimulationoftheposteriortibialnerveduringurodynamicstudiesinpatientswithlowerurinarytractsymptoms AT fritschehansmartin randomizedcrossovercontrolledevaluationofsimultaneousbilateraltranscutaneouselectrostimulationoftheposteriortibialnerveduringurodynamicstudiesinpatientswithlowerurinarytractsymptoms AT zemanflorian randomizedcrossovercontrolledevaluationofsimultaneousbilateraltranscutaneouselectrostimulationoftheposteriortibialnerveduringurodynamicstudiesinpatientswithlowerurinarytractsymptoms AT hubertoni randomizedcrossovercontrolledevaluationofsimultaneousbilateraltranscutaneouselectrostimulationoftheposteriortibialnerveduringurodynamicstudiesinpatientswithlowerurinarytractsymptoms AT haidermaximilian randomizedcrossovercontrolledevaluationofsimultaneousbilateraltranscutaneouselectrostimulationoftheposteriortibialnerveduringurodynamicstudiesinpatientswithlowerurinarytractsymptoms AT picklchristoph randomizedcrossovercontrolledevaluationofsimultaneousbilateraltranscutaneouselectrostimulationoftheposteriortibialnerveduringurodynamicstudiesinpatientswithlowerurinarytractsymptoms AT burgermaximilian randomizedcrossovercontrolledevaluationofsimultaneousbilateraltranscutaneouselectrostimulationoftheposteriortibialnerveduringurodynamicstudiesinpatientswithlowerurinarytractsymptoms AT mayrroman randomizedcrossovercontrolledevaluationofsimultaneousbilateraltranscutaneouselectrostimulationoftheposteriortibialnerveduringurodynamicstudiesinpatientswithlowerurinarytractsymptoms |