Investigating the in vitro steatotic mixture effects of similarly and dissimilarly acting test compounds using an adverse outcome pathway-based approach

Within the EuroMix project, we have previously developed an adverse outcome pathway (AOP)-based in vitro assay toolbox to investigate the combined effects of liver steatosis-inducing compounds in human HepaRG hepatocarcinoma cells. In this study, we applied the toolbox to further investigate mixture...

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Detalles Bibliográficos
Autores principales: Alarcan, Jimmy, de Sousa, Georges, Katsanou, Efrosini S., Spyropoulou, Anastasia, Batakis, Petros, Machera, Kyriaki, Rahmani, Roger, Lampen, Alfonso, Braeuning, Albert, Lichtenstein, Dajana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2021
Materias:
Molecular Toxicology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8748329/
https://www.ncbi.nlm.nih.gov/pubmed/34778935
http://dx.doi.org/10.1007/s00204-021-03182-1

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