Cargando…

Deoxynivalenol induces apoptosis and autophagy in human prostate epithelial cells via PI3K/Akt signaling pathway

Phosphoinositide 3-kinase (PI3K)/protein kinase B (Akt) signaling pathway is one of the most deregulated signaling pathway in prostate cancer. It controls basic processes in cells: cell proliferation and death. Any disturbances in the balance between cell death and survival might result in carcinoge...

Descripción completa

Detalles Bibliográficos
Autores principales:	Kowalska, Karolina, Kozieł, Marta Justyna, Habrowska-Górczyńska, Dominika Ewa, Urbanek, Kinga Anna, Domińska, Kamila, Piastowska-Ciesielska, Agnieszka Wanda
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer Berlin Heidelberg 2021
Materias:	Molecular Toxicology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8748346/ https://www.ncbi.nlm.nih.gov/pubmed/34677630 http://dx.doi.org/10.1007/s00204-021-03176-z

Ejemplares similares

In Vitro Analysis of Deoxynivalenol Influence on Steroidogenesis in Prostate
por: Urbanek, Kinga Anna, et al.
Publicado: (2021)

Deoxynivalenol Modulates the Viability, ROS Production and Apoptosis in Prostate Cancer Cells
por: Habrowska-Górczyńska, Dominika Ewa, et al.
Publicado: (2019)

Mycotoxin Alternariol (AOH) Affects Viability and Motility of Mammary Breast Epithelial Cells
por: Kowalska, Karolina, et al.
Publicado: (2021)

Estrogen Receptor β Participates in Alternariol-Induced Oxidative Stress in Normal Prostate Epithelial Cells
por: Kowalska, Karolina, et al.
Publicado: (2021)

Revealing the Role of Alternariol in the Local Steroidogenesis in Human Prostate Normal and Cancer Cells
por: Urbanek, Kinga Anna, et al.
Publicado: (2023)

Estrogen Receptor α Is Crucial in Zearalenone-Induced Invasion and Migration of Prostate Cancer Cells
por: Kowalska, Karolina, et al.
Publicado: (2018)

ERβ and NFκB—Modulators of Zearalenone-Induced Oxidative Stress in Human Prostate Cancer Cells
por: Kowalska, Karolina, et al.
Publicado: (2020)

The Influence of Angiotensin Peptides on Survival and Motility of Human High-Grade Serous Ovarian Cancer Cells in Serum Starvation Conditions
por: Domińska, Kamila, et al.
Publicado: (2021)

Methylsulfonylmethane sensitizes endometrial cancer cells to doxorubicin
por: Kowalska, Karolina, et al.
Publicado: (2020)

The Impact of Ang-(1-9) and Ang-(3-7) on the Biological Properties of Prostate Cancer Cells by Modulation of Inflammatory and Steroidogenesis Pathway Genes
por: Domińska, Kamila, et al.
Publicado: (2020)

Angiotensin 1–7 modulates molecular and cellular processes central to the pathogenesis of prostate cancer
por: Domińska, Kamila, et al.
Publicado: (2018)

FOXO3a and Its Regulators in Prostate Cancer
por: Habrowska-Górczyńska, Dominika Ewa, et al.
Publicado: (2021)

Claudins: New Players in Human Fertility and Reproductive System Cancers
por: Kozieł, Marta Justyna, et al.
Publicado: (2020)

Nrf2: a main responsive element in cells to mycotoxin-induced toxicity
por: Kozieł, Marta Justyna, et al.
Publicado: (2021)

Angiotensin II and Angiotensin Receptors 1 and 2—Multifunctional System in Cells Biology, What Do We Know?
por: Ziaja, Maksymilian, et al.
Publicado: (2021)

Dioscin-induced autophagy mitigates cell apoptosis through modulation of PI3K/Akt and ERK and JNK signaling pathways in human lung cancer cell lines
por: Hsieh, Ming-Ju, et al.
Publicado: (2013)

Influence of deoxynivalenol and zearalenone on the immunohistochemical expression of oestrogen receptors and liver enzyme genes in vivo in prepubertal gilts
por: Gajęcka, Magdalena, et al.
Publicado: (2023)

Estrogens, Estrogen Receptors and Tumor Microenvironment in Ovarian Cancer
por: Kozieł, Marta Justyna, et al.
Publicado: (2023)

Oestrogens and oestrogen receptors in prostate cancer
por: Kowalska, Karolina, et al.
Publicado: (2016)

Effect of an angiotensin II type 1 receptor blocker on caveolin-1 expression in prostate cancer cells
por: Piastowska-Ciesielska, Agnieszka Wanda, et al.
Publicado: (2012)

Intestinal Barrier, Claudins and Mycotoxins
por: Kozieł, Marta Justyna, et al.
Publicado: (2021)

Activation of autophagy triggers mitochondrial loss and changes acetylation profile relevant for mechanotransduction in bladder cancer cells
por: Jobst, Maximilian, et al.
Publicado: (2022)

Multiparametric assessment of mitochondrial respiratory inhibition in HepG2 and RPTEC/TERT1 cells using a panel of mitochondrial targeting agrochemicals
por: van der Stel, Wanda, et al.
Publicado: (2020)

Canonical, Non-Canonical and Atypical Pathways of Nuclear Factor кb Activation in Preeclampsia
por: Sakowicz, Agata, et al.
Publicado: (2020)

Cell Cycle Status Influences Resistance to Apoptosis Induced by Oxidative Stress in Human Breast Cancer Cells, Which Is Accompanied by Modulation of Autophagy
por: Kluska, Magdalena, et al.
Publicado: (2023)

Combination of Autophagy Selective Therapeutics With Doxil: An Assessment of Pathological Toxicity
por: Helke, Kristi L., et al.
Publicado: (2022)

The Preeclamptic Environment Promotes the Activation of Transcription Factor Kappa B by P53/RSK1 Complex in a HTR8/SVneo Trophoblastic Cell Line
por: Sakowicz, Agata, et al.
Publicado: (2021)

Lithocholic acid induces endoplasmic reticulum stress, autophagy and mitochondrial dysfunction in human prostate cancer cells
por: Gafar, Ahmed A., et al.
Publicado: (2016)

Long-term AZT Exposure Alters the Metabolic Capacity of Cultured Human Lymphoblastoid Cells
por: Olivero, Ofelia A., et al.
Publicado: (2010)

The Glutaredoxin GLRX-21 Functions to Prevent Selenium-Induced Oxidative Stress in Caenorhabditis elegans
por: Morgan, Kathleen L., et al.
Publicado: (2010)

Effects of Perfluoroalkyl Compounds on mRNA Expression Levels of Thyroid Hormone-Responsive Genes in Primary Cultures of Avian Neuronal Cells
por: Vongphachan, Viengtha, et al.
Publicado: (2011)

Chloramphenicol Causes Mitochondrial Stress, Decreases ATP Biosynthesis, Induces Matrix Metalloproteinase-13 Expression, and Solid-Tumor Cell Invasion
por: Li, Ching-Hao, et al.
Publicado: (2010)

The effects of sodium diethyldithiocarbamate in fibroblasts V79 cells in relation to cytotoxicity, antioxidative enzymes, glutathione, and apoptosis
por: Rahden-Staroń, I., et al.
Publicado: (2012)

Diquat causes caspase-independent cell death in SH-SY5Y cells by production of ROS independently of mitochondria
por: Nisar, R., et al.
Publicado: (2015)

Metabolically inert perfluorinated fatty acids directly activate uncoupling protein 1 in brown-fat mitochondria
por: Shabalina, Irina G., et al.
Publicado: (2015)

2,3,7,8 Tetrachlorodibenzo-p-dioxin-induced RNA abundance changes identify Ackr3, Col18a1, Cyb5a and Glud1 as candidate mediators of toxicity
por: Watson, John D., et al.
Publicado: (2016)

Accelerated telomere shortening in peripheral blood lymphocytes after occupational polychlorinated biphenyls exposure
por: Ziegler, Susanne, et al.
Publicado: (2016)

Activation of the Nrf2-ARE pathway by the Alternaria alternata mycotoxins altertoxin I and II
por: Jarolim, Katharina, et al.
Publicado: (2016)

Comparative transcriptomic analyses to scrutinize the assumption that genotoxic PAHs exert effects via a common mode of action
por: Labib, S., et al.
Publicado: (2015)

PFOS induces proliferation, cell-cycle progression, and malignant phenotype in human breast epithelial cells
por: Pierozan, Paula, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_te3hq40knb4ekod38pu9aopcob