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Accurate characterization of β-amyloid (Aβ40, Aβ42) standards using species-specific isotope dilution by means of HPLC-ICP-MS/MS

The amyloid β peptide, as one of the main components in senile plaque, represents a defining pathological feature for Alzheimer’s disease, and is therefore commonly used as a biomarker for this disease in clinical analysis. However, the selection of suitable standards is limited here, since only a f...

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Detalles Bibliográficos
Autores principales: Schaier, Martin, Hermann, Gerrit, Koellensperger, Gunda, Theiner, Sarah
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8748378/
https://www.ncbi.nlm.nih.gov/pubmed/34355254
http://dx.doi.org/10.1007/s00216-021-03571-6