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Intrinsically disordered proteins identified in the aggregate proteome serve as biomarkers of neurodegeneration

A protein’s structure is determined by its amino acid sequence and post-translational modifications, and provides the basis for its physiological functions. Across all organisms, roughly a third of the proteome comprises proteins that contain highly unstructured or intrinsically disordered regions....

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Detalles Bibliográficos
Autores principales: Ayyadevara, Srinivas, Ganne, Akshatha, Balasubramaniam, Meenakshisundaram, Shmookler Reis, Robert J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8748380/
https://www.ncbi.nlm.nih.gov/pubmed/34347206
http://dx.doi.org/10.1007/s11011-021-00791-8