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Intrinsically disordered proteins identified in the aggregate proteome serve as biomarkers of neurodegeneration
A protein’s structure is determined by its amino acid sequence and post-translational modifications, and provides the basis for its physiological functions. Across all organisms, roughly a third of the proteome comprises proteins that contain highly unstructured or intrinsically disordered regions....
Autores principales: | Ayyadevara, Srinivas, Ganne, Akshatha, Balasubramaniam, Meenakshisundaram, Shmookler Reis, Robert J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer US
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8748380/ https://www.ncbi.nlm.nih.gov/pubmed/34347206 http://dx.doi.org/10.1007/s11011-021-00791-8 |
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