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Role of cardiolipins, mitochondria, and autophagy in the differentiation process activated by all-trans retinoic acid in acute promyelocytic leukemia

The role played by lipids in the process of granulocytic differentiation activated by all-trans retinoic acid (ATRA) in Acute-Promyelocytic-Leukemia (APL) blasts is unknown. The process of granulocytic differentiation activated by ATRA in APL blasts is recapitulated in the NB4 cell-line, which is ch...

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Detalles Bibliográficos
Autores principales: Gianni’, Maurizio, Goracci, Laura, Schlaefli, Anna, Di Veroli, Alessandra, Kurosaki, Mami, Guarrera, Luca, Bolis, Marco, Foglia, Marika, Lupi, Monica, Tschan, Mario P., Cruciani, Gabriele, Terao, Mineko, Garattini, Enrico
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8748438/
https://www.ncbi.nlm.nih.gov/pubmed/35013142
http://dx.doi.org/10.1038/s41419-021-04476-z