Expression of type I interferon-associated genes at antiretroviral therapy interruption predicts HIV virological rebound

Although certain individuals with HIV infection can stop antiretroviral therapy (ART) without viral load rebound, the mechanisms under-pinning ‘post-treatment control’ remain unclear. Using RNA-Seq we explored CD4 T cell gene expression to identify evidence of a mechanism that might underpin virolog...

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Detalles Bibliográficos
Autores principales: Zacharopoulou, P., Marchi, E., Ogbe, A., Robinson, N., Brown, H., Jones, M., Parolini, L., Pace, M., Grayson, N., Kaleebu, P., Rees, H., Fidler, S., Goulder, P., Klenerman, P., Frater, J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8748440/
https://www.ncbi.nlm.nih.gov/pubmed/35013427
http://dx.doi.org/10.1038/s41598-021-04212-9

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