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A bispecific monomeric nanobody induces spike trimer dimers and neutralizes SARS-CoV-2 in vivo

Antibodies binding to the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike have therapeutic promise, but emerging variants show the potential for virus escape. This emphasizes the need for therapeutic molecules with distinct and novel neutralization mechanisms. Here we describe the...

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Detalles Bibliográficos
Autores principales:	Hanke, Leo, Das, Hrishikesh, Sheward, Daniel J., Perez Vidakovics, Laura, Urgard, Egon, Moliner-Morro, Ainhoa, Kim, Changil, Karl, Vivien, Pankow, Alec, Smith, Natalie L., Porebski, Bartlomiej, Fernandez-Capetillo, Oscar, Sezgin, Erdinc, Pedersen, Gabriel K., Coquet, Jonathan M., Hällberg, B. Martin, Murrell, Ben, McInerney, Gerald M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8748511/ https://www.ncbi.nlm.nih.gov/pubmed/35013189 http://dx.doi.org/10.1038/s41467-021-27610-z

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