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The differential effects of tumor burdens on predicting the net benefits of ssCART-19 cell treatment on r/r B-ALL patients

The tumor burden (TB) is significantly related to the severity of cytokine release syndrome (CRS) caused by CAR-T cells, but its correlation with therapeutic efficacy has not been systematically studied. This study focused on the effects of the TB level on both the safety and efficacy of ssCART-19 a...

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Detalles Bibliográficos
Autores principales:	Li, Minghao, Xue, Sheng-Li, Tang, Xiaowen, Xu, Jiayu, Chen, Suning, Han, Yue, Qiu, Huiying, Miao, Miao, Xu, Nan, Tan, Jingwen, Kang, Liqing, Yu, Zhou, Lou, Xiaoyan, Xu, Yang, Chen, Jia, Yan, Zhiqiang, Feng, Weixing, Wu, Depei, Yu, Lei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8748521/ https://www.ncbi.nlm.nih.gov/pubmed/35013456 http://dx.doi.org/10.1038/s41598-021-04296-3

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