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TGF-βRII regulates glucose metabolism in oral cancer-associated fibroblasts via promoting PKM2 nuclear translocation

Cancer-associated fibroblasts (CAFs) are highly heterogeneous and differentiated stromal cells that promote tumor progression via remodeling of extracellular matrix, maintenance of stemness, angiogenesis, and modulation of tumor metabolism. Aerobic glycolysis is characterized by an increased uptake...

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Detalles Bibliográficos
Autores principales:	Wu, Fanglong, Wang, Shimeng, Zeng, Qingxiang, Liu, Junjiang, Yang, Jin, Mu, Jingtian, Xu, Hongdang, Wu, Lanyan, Gao, Qinghong, He, Xin, Liu, Ying, Zhou, Hongmei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8748622/ https://www.ncbi.nlm.nih.gov/pubmed/35013150 http://dx.doi.org/10.1038/s41420-021-00804-6

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