Targeting necroptosis in muscle fibers ameliorates inflammatory myopathies

Muscle cell death in polymyositis is induced by CD8(+) cytotoxic T lymphocytes. We hypothesized that the injured muscle fibers release pro-inflammatory molecules, which would further accelerate CD8(+) cytotoxic T lymphocytes-induced muscle injury, and inhibition of the cell death of muscle fibers co...

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Detalles Bibliográficos
Autores principales: Kamiya, Mari, Mizoguchi, Fumitaka, Kawahata, Kimito, Wang, Dengli, Nishibori, Masahiro, Day, Jessica, Louis, Cynthia, Wicks, Ian P., Kohsaka, Hitoshi, Yasuda, Shinsuke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8748624/
https://www.ncbi.nlm.nih.gov/pubmed/35013338
http://dx.doi.org/10.1038/s41467-021-27875-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8748624/
https://www.ncbi.nlm.nih.gov/pubmed/35013338
http://dx.doi.org/10.1038/s41467-021-27875-4

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