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Targeting necroptosis in muscle fibers ameliorates inflammatory myopathies

Muscle cell death in polymyositis is induced by CD8(+) cytotoxic T lymphocytes. We hypothesized that the injured muscle fibers release pro-inflammatory molecules, which would further accelerate CD8(+) cytotoxic T lymphocytes-induced muscle injury, and inhibition of the cell death of muscle fibers co...

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Detalles Bibliográficos
Autores principales:	Kamiya, Mari, Mizoguchi, Fumitaka, Kawahata, Kimito, Wang, Dengli, Nishibori, Masahiro, Day, Jessica, Louis, Cynthia, Wicks, Ian P., Kohsaka, Hitoshi, Yasuda, Shinsuke
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8748624/ https://www.ncbi.nlm.nih.gov/pubmed/35013338 http://dx.doi.org/10.1038/s41467-021-27875-4

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