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Whole blood transcriptional signatures associated with rapid antidepressant response to ketamine in patients with treatment resistant depression
Ketamine has rapid and sustained antidepressant effects in patients with treatment-resistant depression (TRD). However, the underlying mechanisms of action are not well understood. There is increasing evidence that TRD is associated with a pro-inflammatory state and that ketamine may inhibit inflamm...
Autores principales: | Cathomas, Flurin, Bevilacqua, Laura, Ramakrishnan, Aarthi, Kronman, Hope, Costi, Sara, Schneider, Molly, Chan, Kenny L., Li, Long, Nestler, Eric J., Shen, Li, Charney, Dennis S., Russo, Scott J., Murrough, James W. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8748646/ https://www.ncbi.nlm.nih.gov/pubmed/35013133 http://dx.doi.org/10.1038/s41398-021-01712-0 |
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