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Single-cell analysis of human primary prostate cancer reveals the heterogeneity of tumor-associated epithelial cell states

Prostate cancer is the second most common malignancy in men worldwide and consists of a mixture of tumor and non-tumor cell types. To characterize the prostate cancer tumor microenvironment, we perform single-cell RNA-sequencing on prostate biopsies, prostatectomy specimens, and patient-derived orga...

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Detalles Bibliográficos
Autores principales: Song, Hanbing, Weinstein, Hannah N. W., Allegakoen, Paul, Wadsworth, Marc H., Xie, Jamie, Yang, Heiko, Castro, Ethan A., Lu, Kevin L., Stohr, Bradley A., Feng, Felix Y., Carroll, Peter R., Wang, Bruce, Cooperberg, Matthew R., Shalek, Alex K., Huang, Franklin W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8748675/
https://www.ncbi.nlm.nih.gov/pubmed/35013146
http://dx.doi.org/10.1038/s41467-021-27322-4