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Cross-classification between self-rated health and health status: longitudinal analyses of all-cause mortality and leading causes of death in the UK

Risk stratification is an important public health priority that is central to clinical decision making and resource allocation. The aim of this study was to examine how different combinations of self-rated and objective health status predict all-cause mortality and leading causes of death in the UK....

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Autores principales: Mutz, Julian, Lewis, Cathryn M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8748682/
https://www.ncbi.nlm.nih.gov/pubmed/35013388
http://dx.doi.org/10.1038/s41598-021-04016-x
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author Mutz, Julian
Lewis, Cathryn M.
author_facet Mutz, Julian
Lewis, Cathryn M.
author_sort Mutz, Julian
collection PubMed
description Risk stratification is an important public health priority that is central to clinical decision making and resource allocation. The aim of this study was to examine how different combinations of self-rated and objective health status predict all-cause mortality and leading causes of death in the UK. The UK Biobank study recruited > 500,000 participants between 2006 and 2010. Self-rated health was assessed using a single-item question and health status was derived from medical history, including data on 81 cancer and 443 non-cancer illnesses. Analyses included > 370,000 middle-aged and older adults with a median follow-up of 11.75 (IQR = 1.4) years, yielding 4,320,270 person-years of follow-up. Compared to individuals with excellent self-rated health and favourable health status, individuals with other combinations of self-rated and objective health status had a greater mortality risk, with hazard ratios ranging from HR = 1.22 (95% CI 1.15–1.29, P(Bonf.) < 0.001) for individuals with good self-rated health and favourable health status to HR = 7.14 (95% CI 6.70–7.60, P(Bonf.) < 0.001) for individuals with poor self-rated health and unfavourable health status. Our findings highlight that self-rated health captures additional health-related information and should be more widely assessed. The cross-classification between self-rated health and health status represents a straightforward metric for risk stratification, with applications to population health, clinical decision making and resource allocation.
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spelling pubmed-87486822022-01-11 Cross-classification between self-rated health and health status: longitudinal analyses of all-cause mortality and leading causes of death in the UK Mutz, Julian Lewis, Cathryn M. Sci Rep Article Risk stratification is an important public health priority that is central to clinical decision making and resource allocation. The aim of this study was to examine how different combinations of self-rated and objective health status predict all-cause mortality and leading causes of death in the UK. The UK Biobank study recruited > 500,000 participants between 2006 and 2010. Self-rated health was assessed using a single-item question and health status was derived from medical history, including data on 81 cancer and 443 non-cancer illnesses. Analyses included > 370,000 middle-aged and older adults with a median follow-up of 11.75 (IQR = 1.4) years, yielding 4,320,270 person-years of follow-up. Compared to individuals with excellent self-rated health and favourable health status, individuals with other combinations of self-rated and objective health status had a greater mortality risk, with hazard ratios ranging from HR = 1.22 (95% CI 1.15–1.29, P(Bonf.) < 0.001) for individuals with good self-rated health and favourable health status to HR = 7.14 (95% CI 6.70–7.60, P(Bonf.) < 0.001) for individuals with poor self-rated health and unfavourable health status. Our findings highlight that self-rated health captures additional health-related information and should be more widely assessed. The cross-classification between self-rated health and health status represents a straightforward metric for risk stratification, with applications to population health, clinical decision making and resource allocation. Nature Publishing Group UK 2022-01-10 /pmc/articles/PMC8748682/ /pubmed/35013388 http://dx.doi.org/10.1038/s41598-021-04016-x Text en © The Author(s) 2022 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Article
Mutz, Julian
Lewis, Cathryn M.
Cross-classification between self-rated health and health status: longitudinal analyses of all-cause mortality and leading causes of death in the UK
title Cross-classification between self-rated health and health status: longitudinal analyses of all-cause mortality and leading causes of death in the UK
title_full Cross-classification between self-rated health and health status: longitudinal analyses of all-cause mortality and leading causes of death in the UK
title_fullStr Cross-classification between self-rated health and health status: longitudinal analyses of all-cause mortality and leading causes of death in the UK
title_full_unstemmed Cross-classification between self-rated health and health status: longitudinal analyses of all-cause mortality and leading causes of death in the UK
title_short Cross-classification between self-rated health and health status: longitudinal analyses of all-cause mortality and leading causes of death in the UK
title_sort cross-classification between self-rated health and health status: longitudinal analyses of all-cause mortality and leading causes of death in the uk
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8748682/
https://www.ncbi.nlm.nih.gov/pubmed/35013388
http://dx.doi.org/10.1038/s41598-021-04016-x
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