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Cross-classification between self-rated health and health status: longitudinal analyses of all-cause mortality and leading causes of death in the UK
Risk stratification is an important public health priority that is central to clinical decision making and resource allocation. The aim of this study was to examine how different combinations of self-rated and objective health status predict all-cause mortality and leading causes of death in the UK....
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8748682/ https://www.ncbi.nlm.nih.gov/pubmed/35013388 http://dx.doi.org/10.1038/s41598-021-04016-x |
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author | Mutz, Julian Lewis, Cathryn M. |
author_facet | Mutz, Julian Lewis, Cathryn M. |
author_sort | Mutz, Julian |
collection | PubMed |
description | Risk stratification is an important public health priority that is central to clinical decision making and resource allocation. The aim of this study was to examine how different combinations of self-rated and objective health status predict all-cause mortality and leading causes of death in the UK. The UK Biobank study recruited > 500,000 participants between 2006 and 2010. Self-rated health was assessed using a single-item question and health status was derived from medical history, including data on 81 cancer and 443 non-cancer illnesses. Analyses included > 370,000 middle-aged and older adults with a median follow-up of 11.75 (IQR = 1.4) years, yielding 4,320,270 person-years of follow-up. Compared to individuals with excellent self-rated health and favourable health status, individuals with other combinations of self-rated and objective health status had a greater mortality risk, with hazard ratios ranging from HR = 1.22 (95% CI 1.15–1.29, P(Bonf.) < 0.001) for individuals with good self-rated health and favourable health status to HR = 7.14 (95% CI 6.70–7.60, P(Bonf.) < 0.001) for individuals with poor self-rated health and unfavourable health status. Our findings highlight that self-rated health captures additional health-related information and should be more widely assessed. The cross-classification between self-rated health and health status represents a straightforward metric for risk stratification, with applications to population health, clinical decision making and resource allocation. |
format | Online Article Text |
id | pubmed-8748682 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Nature Publishing Group UK |
record_format | MEDLINE/PubMed |
spelling | pubmed-87486822022-01-11 Cross-classification between self-rated health and health status: longitudinal analyses of all-cause mortality and leading causes of death in the UK Mutz, Julian Lewis, Cathryn M. Sci Rep Article Risk stratification is an important public health priority that is central to clinical decision making and resource allocation. The aim of this study was to examine how different combinations of self-rated and objective health status predict all-cause mortality and leading causes of death in the UK. The UK Biobank study recruited > 500,000 participants between 2006 and 2010. Self-rated health was assessed using a single-item question and health status was derived from medical history, including data on 81 cancer and 443 non-cancer illnesses. Analyses included > 370,000 middle-aged and older adults with a median follow-up of 11.75 (IQR = 1.4) years, yielding 4,320,270 person-years of follow-up. Compared to individuals with excellent self-rated health and favourable health status, individuals with other combinations of self-rated and objective health status had a greater mortality risk, with hazard ratios ranging from HR = 1.22 (95% CI 1.15–1.29, P(Bonf.) < 0.001) for individuals with good self-rated health and favourable health status to HR = 7.14 (95% CI 6.70–7.60, P(Bonf.) < 0.001) for individuals with poor self-rated health and unfavourable health status. Our findings highlight that self-rated health captures additional health-related information and should be more widely assessed. The cross-classification between self-rated health and health status represents a straightforward metric for risk stratification, with applications to population health, clinical decision making and resource allocation. Nature Publishing Group UK 2022-01-10 /pmc/articles/PMC8748682/ /pubmed/35013388 http://dx.doi.org/10.1038/s41598-021-04016-x Text en © The Author(s) 2022 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . |
spellingShingle | Article Mutz, Julian Lewis, Cathryn M. Cross-classification between self-rated health and health status: longitudinal analyses of all-cause mortality and leading causes of death in the UK |
title | Cross-classification between self-rated health and health status: longitudinal analyses of all-cause mortality and leading causes of death in the UK |
title_full | Cross-classification between self-rated health and health status: longitudinal analyses of all-cause mortality and leading causes of death in the UK |
title_fullStr | Cross-classification between self-rated health and health status: longitudinal analyses of all-cause mortality and leading causes of death in the UK |
title_full_unstemmed | Cross-classification between self-rated health and health status: longitudinal analyses of all-cause mortality and leading causes of death in the UK |
title_short | Cross-classification between self-rated health and health status: longitudinal analyses of all-cause mortality and leading causes of death in the UK |
title_sort | cross-classification between self-rated health and health status: longitudinal analyses of all-cause mortality and leading causes of death in the uk |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8748682/ https://www.ncbi.nlm.nih.gov/pubmed/35013388 http://dx.doi.org/10.1038/s41598-021-04016-x |
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