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Structural assessment of HLA-A2-restricted SARS-CoV-2 spike epitopes recognized by public and private T-cell receptors
T cells play a vital role in combatting SARS-CoV-2 and forming long-term memory responses. Whereas extensive structural information is available on neutralizing antibodies against SARS-CoV-2, such information on SARS-CoV-2-specific T-cell receptors (TCRs) bound to their peptide–MHC targets is lackin...
Autores principales: | Wu, Daichao, Kolesnikov, Alexander, Yin, Rui, Guest, Johnathan D., Gowthaman, Ragul, Shmelev, Anton, Serdyuk, Yana, Dianov, Dmitry V., Efimov, Grigory A., Pierce, Brian G., Mariuzza, Roy A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8748687/ https://www.ncbi.nlm.nih.gov/pubmed/35013235 http://dx.doi.org/10.1038/s41467-021-27669-8 |
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