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Structural assessment of HLA-A2-restricted SARS-CoV-2 spike epitopes recognized by public and private T-cell receptors

T cells play a vital role in combatting SARS-CoV-2 and forming long-term memory responses. Whereas extensive structural information is available on neutralizing antibodies against SARS-CoV-2, such information on SARS-CoV-2-specific T-cell receptors (TCRs) bound to their peptide–MHC targets is lackin...

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Detalles Bibliográficos
Autores principales: Wu, Daichao, Kolesnikov, Alexander, Yin, Rui, Guest, Johnathan D., Gowthaman, Ragul, Shmelev, Anton, Serdyuk, Yana, Dianov, Dmitry V., Efimov, Grigory A., Pierce, Brian G., Mariuzza, Roy A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8748687/
https://www.ncbi.nlm.nih.gov/pubmed/35013235
http://dx.doi.org/10.1038/s41467-021-27669-8

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