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Effects of intracellular calcium accumulation on proteins encoded by the major genes underlying amyotrophic lateral sclerosis
The aetiology of Amyotrophic Lateral Sclerosis (ALS) is still poorly understood. The discovery of genetic forms of ALS pointed out the mechanisms underlying this pathology, but also showed how complex these mechanisms are. Excitotoxicity is strongly suspected to play a role in ALS pathogenesis. Exci...
Autores principales: | , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8748718/ https://www.ncbi.nlm.nih.gov/pubmed/35013445 http://dx.doi.org/10.1038/s41598-021-04267-8 |