Effects of intracellular calcium accumulation on proteins encoded by the major genes underlying amyotrophic lateral sclerosis

The aetiology of Amyotrophic Lateral Sclerosis (ALS) is still poorly understood. The discovery of genetic forms of ALS pointed out the mechanisms underlying this pathology, but also showed how complex these mechanisms are. Excitotoxicity is strongly suspected to play a role in ALS pathogenesis. Exci...

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Detalles Bibliográficos
Autores principales: De Marco, Giovanni, Lomartire, Annarosa, Manera, Umberto, Canosa, Antonio, Grassano, Maurizio, Casale, Federico, Fuda, Giuseppe, Salamone, Paolina, Rinaudo, Maria Teresa, Colombatto, Sebastiano, Moglia, Cristina, Chiò, Adriano, Calvo, Andrea
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8748718/
https://www.ncbi.nlm.nih.gov/pubmed/35013445
http://dx.doi.org/10.1038/s41598-021-04267-8

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