Polygenic contribution to the relationship of loneliness and social isolation with schizophrenia

Previous research suggests an association of loneliness and social isolation (LNL-ISO) with schizophrenia. Here, we demonstrate a LNL-ISO polygenic score contribution to schizophrenia risk in an independent case-control sample (N = 3,488). We then subset schizophrenia predisposing variation based on...

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Detalles Bibliográficos
Autores principales: Andreu-Bernabeu, Álvaro, Díaz-Caneja, Covadonga M., Costas, Javier, De Hoyos, Lucía, Stella, Carol, Gurriarán, Xaquín, Alloza, Clara, Fañanás, Lourdes, Bobes, Julio, González-Pinto, Ana, Crespo-Facorro, Benedicto, Martorell, Lourdes, Vilella, Elisabet, Muntané, Gerard, Nacher, Juan, Molto, María Dolores, Aguilar, Eduardo Jesús, Parellada, Mara, Arango, Celso, González-Peñas, Javier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8748758/
https://www.ncbi.nlm.nih.gov/pubmed/35013163
http://dx.doi.org/10.1038/s41467-021-27598-6

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