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Mechanical force promotes dimethylarginine dimethylaminohydrolase 1-mediated hydrolysis of the metabolite asymmetric dimethylarginine to enhance bone formation

Mechanical force is critical for the development and remodeling of bone. Here we report that mechanical force regulates the production of the metabolite asymmetric dimethylarginine (ADMA) via regulating the hydrolytic enzyme dimethylarginine dimethylaminohydrolase 1 (Ddah1) expression in osteoblasts...

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Detalles Bibliográficos
Autores principales:	Xie, Ziang, Hou, Lei, Shen, Shuying, Wu, Yizheng, Wang, Jian, Jie, Zhiwei, Zhao, Xiangde, Li, Xiang, Zhang, Xuyang, Chen, Junxin, Xu, Wenbin, Ning, Lei, Ma, Qingliang, Wang, Shiyu, Wang, Haoming, Yuan, Putao, Fang, Xiangqian, Qin, An, Fan, Shunwu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8748781/ https://www.ncbi.nlm.nih.gov/pubmed/35013196 http://dx.doi.org/10.1038/s41467-021-27629-2

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