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The immune-suppressive landscape in lepromatous leprosy revealed by single-cell RNA sequencing
Lepromatous leprosy (L-LEP), caused by the massive proliferation of Mycobacterium leprae primarily in macrophages, is an ideal disease model for investigating the molecular mechanism of intracellular bacteria evading or modulating host immune response. Here, we performed single-cell RNA sequencing o...
Autores principales: | Mi, Zihao, Wang, Zhenzhen, Xue, Xiaotong, Liu, Tingting, Wang, Chuan, Sun, Lele, Yu, Gongqi, Zhang, Yuan, Shi, Peidian, Sun, Yonghu, Yang, Yongliang, Ma, Shanshan, Wang, Zhe, Yu, Yueqian, Liu, Jianjun, Liu, Hong, Zhang, Furen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Singapore
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8748782/ https://www.ncbi.nlm.nih.gov/pubmed/35013182 http://dx.doi.org/10.1038/s41421-021-00353-3 |
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