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Structure of putative tumor suppressor ALDH1L1

Putative tumor suppressor ALDH1L1, the product of natural fusion of three unrelated genes, regulates folate metabolism by catalyzing NADP(+)-dependent conversion of 10-formyltetrahydrofolate to tetrahydrofolate and CO(2). Cryo-EM structures of tetrameric rat ALDH1L1 revealed the architecture and fun...

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Detalles Bibliográficos
Autores principales:	Tsybovsky, Yaroslav, Sereda, Valentin, Golczak, Marcin, Krupenko, Natalia I., Krupenko, Sergey A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8748788/ https://www.ncbi.nlm.nih.gov/pubmed/35013550 http://dx.doi.org/10.1038/s42003-021-02963-9

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