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Cryo-EM structure of native human thyroglobulin

The thyroglobulin (TG) protein is essential to thyroid hormone synthesis, plays a vital role in the regulation of metabolism, development and growth and serves as intraglandular iodine storage. Its architecture is conserved among vertebrates. Synthesis of triiodothyronine (T(3)) and thyroxine (T(4))...

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Detalles Bibliográficos
Autores principales: Adaixo, Ricardo, Steiner, Eva M., Righetto, Ricardo D., Schmidt, Alexander, Stahlberg, Henning, Taylor, Nicholas M. I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8748809/
https://www.ncbi.nlm.nih.gov/pubmed/35013249
http://dx.doi.org/10.1038/s41467-021-27693-8