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Cryo-EM structure of native human thyroglobulin
The thyroglobulin (TG) protein is essential to thyroid hormone synthesis, plays a vital role in the regulation of metabolism, development and growth and serves as intraglandular iodine storage. Its architecture is conserved among vertebrates. Synthesis of triiodothyronine (T(3)) and thyroxine (T(4))...
Autores principales: | Adaixo, Ricardo, Steiner, Eva M., Righetto, Ricardo D., Schmidt, Alexander, Stahlberg, Henning, Taylor, Nicholas M. I. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8748809/ https://www.ncbi.nlm.nih.gov/pubmed/35013249 http://dx.doi.org/10.1038/s41467-021-27693-8 |
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