Synthetic prodrug design enables biocatalytic activation in mice to elicit tumor growth suppression

Considering the intrinsic toxicities of transition metals, their incorporation into drug therapies must operate at minimal amounts while ensuring adequate catalytic activity within complex biological systems. As a way to address this issue, this study investigates the design of synthetic prodrugs th...

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Detalles Bibliográficos
Autores principales: Nasibullin, Igor, Smirnov, Ivan, Ahmadi, Peni, Vong, Kenward, Kurbangalieva, Almira, Tanaka, Katsunori
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8748823/
https://www.ncbi.nlm.nih.gov/pubmed/35013295
http://dx.doi.org/10.1038/s41467-021-27804-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8748823/
https://www.ncbi.nlm.nih.gov/pubmed/35013295
http://dx.doi.org/10.1038/s41467-021-27804-5

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