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Synthetic prodrug design enables biocatalytic activation in mice to elicit tumor growth suppression
Considering the intrinsic toxicities of transition metals, their incorporation into drug therapies must operate at minimal amounts while ensuring adequate catalytic activity within complex biological systems. As a way to address this issue, this study investigates the design of synthetic prodrugs th...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8748823/ https://www.ncbi.nlm.nih.gov/pubmed/35013295 http://dx.doi.org/10.1038/s41467-021-27804-5 |