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An assembly of nuclear bodies associates with the active VSG expression site in African trypanosomes

A Variant Surface Glycoprotein (VSG) coat protects bloodstream form Trypanosoma brucei. Prodigious amounts of VSG mRNA (~7-10% total) are generated from a single RNA polymerase I (Pol I) transcribed VSG expression site (ES), necessitating extremely high levels of localised splicing. We show that spl...

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Detalles Bibliográficos
Autores principales:	Budzak, James, Jones, Robert, Tschudi, Christian, Kolev, Nikolay G., Rudenko, Gloria
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8748868/ https://www.ncbi.nlm.nih.gov/pubmed/35013170 http://dx.doi.org/10.1038/s41467-021-27625-6

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