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Effects of azithromycin on bronchial remodeling in the natural model of severe neutrophilic asthma in horses
Steroid resistance in asthma has been associated with neutrophilic inflammation and severe manifestations of the disease. Macrolide add-on therapy can improve the quality of life and the exacerbation rate in refractory cases, possibly with greater effectiveness in neutrophilic phenotypes. The mechan...
Autores principales: | Mainguy-Seers, Sophie, Boivin, Roxane, Pourali Dogaheh, Sheila, Beaudry, Francis, Hélie, Pierre, Bonilla, Alvaro G., Martin, James G., Lavoie, Jean-Pierre |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8748876/ https://www.ncbi.nlm.nih.gov/pubmed/35013387 http://dx.doi.org/10.1038/s41598-021-03955-9 |
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