Cross-reactive memory T cells associate with protection against SARS-CoV-2 infection in COVID-19 contacts

Cross-reactive immune responses to SARS-CoV-2 have been observed in pre-pandemic cohorts and proposed to contribute to host protection. Here we assess 52 COVID-19 household contacts to capture immune responses at the earliest timepoints after SARS-CoV-2 exposure. Using a dual cytokine FLISpot assay...

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Detalles Bibliográficos
Autores principales: Kundu, Rhia, Narean, Janakan Sam, Wang, Lulu, Fenn, Joseph, Pillay, Timesh, Fernandez, Nieves Derqui, Conibear, Emily, Koycheva, Aleksandra, Davies, Megan, Tolosa-Wright, Mica, Hakki, Seran, Varro, Robert, McDermott, Eimear, Hammett, Sarah, Cutajar, Jessica, Thwaites, Ryan S., Parker, Eleanor, Rosadas, Carolina, McClure, Myra, Tedder, Richard, Taylor, Graham P., Dunning, Jake, Lalvani, Ajit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8748880/
https://www.ncbi.nlm.nih.gov/pubmed/35013199
http://dx.doi.org/10.1038/s41467-021-27674-x

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