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Targeted editing and evolution of engineered ribosomes in vivo by filtered editing
Genome editing technologies introduce targeted chromosomal modifications in organisms yet are constrained by the inability to selectively modify repetitive genetic elements. Here we describe filtered editing, a genome editing method that embeds group 1 self-splicing introns into repetitive genetic e...
Autores principales: | Radford, Felix, Elliott, Shane D., Schepartz, Alanna, Isaacs, Farren J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8748908/ https://www.ncbi.nlm.nih.gov/pubmed/35013328 http://dx.doi.org/10.1038/s41467-021-27836-x |
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