Cargando…

Neurokinin-1 receptor promotes non-small cell lung cancer progression through transactivation of EGFR

Despite the great advances in target therapy, lung cancer remains the top cause of cancer-related death worldwide. G protein-coupled receptor neurokinin-1 (NK1R) is shown to play multiple roles in various cancers; however, the pathological roles and clinical implication in lung cancer are unclarifie...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhang, Xiao-Wei, Li, Lin, Hu, Wen-Qian, Hu, Ming-Ning, Tao, Yan, Hu, Hui, Miao, Xiao-Kang, Yang, Wen-Le, Zhu, Qiong, Mou, Ling-Yun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8748918/ https://www.ncbi.nlm.nih.gov/pubmed/35013118 http://dx.doi.org/10.1038/s41419-021-04485-y

Ejemplares similares

Neurokinin-1 receptor drives PKCɑ-AURKA/N-Myc signaling to facilitate the neuroendocrine progression of prostate cancer
por: Zhang, Xiao-Wei, et al.
Publicado: (2023)

EGFR transactivation contributes to neuroinflammation in Streptococcus suis meningitis
por: Yang, Xiao-Pei, et al.
Publicado: (2016)

EGFR transactivates RON to drive oncogenic crosstalk
por: Franco Nitta, Carolina, et al.
Publicado: (2021)

Structural insights into the activation of neurokinin 2 receptor by neurokinin A
por: Sun, Wenjing, et al.
Publicado: (2022)

High expression of substance P and its receptor neurokinin-1 receptor in colorectal cancer is associated with tumor progression and prognosis
por: Chen, Xiao-Yi, et al.
Publicado: (2016)

Rapamycin Induces Transactivation of the EGFR and Increases Cell Survival
por: Chaturvedi, Deepti, et al.
Publicado: (2009)

LncRNA ARAP1‐AS2 promotes high glucose‐induced human proximal tubular cell injury via persistent transactivation of the EGFR by interacting with ARAP1
por: Li, Xin, et al.
Publicado: (2020)

Brk/PTK6 Sustains Activated EGFR Signaling through Inhibiting EGFR Degradation and Transactivating EGFR
por: Li, X, et al.
Publicado: (2012)

Knockdown of neurokinin-1 receptor expression by small interfering RNA prevents the development of allergic rhinitis in rats
por: Wang, Hong, et al.
Publicado: (2013)

GPR54 (KISS1R) Transactivates EGFR to Promote Breast Cancer Cell Invasiveness
por: Zajac, Mateusz, et al.
Publicado: (2011)

Transactivation of EGFR by LPS Induces COX-2 Expression in Enterocytes
por: McElroy, Steven J., et al.
Publicado: (2012)

Hepatocellular carcinoma chemoprevention by targeting the angiotensin-converting enzyme and EGFR transactivation
por: Crouchet, Emilie, et al.
Publicado: (2022)

Long noncoding RNA ANRIL could be transactivated by c-Myc and promote tumor progression of non-small-cell lung cancer
por: Lu, Yi, et al.
Publicado: (2016)

Synaptic Connections of the Neurokinin 1 Receptor-Like Immunoreactive Neurons in the Rat Medullary Dorsal Horn
por: Qi, Jian, et al.
Publicado: (2011)

High Glucose Promotes Pancreatic Cancer Cell Proliferation via the Induction of EGF Expression and Transactivation of EGFR
por: Han, Liang, et al.
Publicado: (2011)

Sharpin promotes hepatocellular carcinoma progression via transactivation of Versican expression
por: Tanaka, Y, et al.
Publicado: (2016)

DNA methylation modifier LSH inhibits p53 ubiquitination and transactivates p53 to promote lipid metabolism
por: Chen, Ling, et al.
Publicado: (2019)

HMGA1 promotes gastric cancer growth and metastasis by transactivating SUZ12 and CCDC43 expression
por: Yang, Qiong, et al.
Publicado: (2021)

Lysophosphatidic Acid–Induced EGFR Transactivation Promotes Gastric Cancer Cell DNA Replication by Stabilizing Geminin in the S Phase
por: Zhao, Haile, et al.
Publicado: (2021)

IKKα contributes to UVB-induced VEGF expression by regulating AP-1 transactivation
por: Dong, Wen, et al.
Publicado: (2012)

Neurokinin-1 Receptor Activation in Globus Pallidus
por: Chen, Lei, et al.
Publicado: (2009)

JMJD2A promotes the Warburg effect and nasopharyngeal carcinoma progression by transactivating LDHA expression
por: Su, Yi, et al.
Publicado: (2017)

Nuclear PKM2 regulates β-catenin transactivation upon EGFR activation
por: Yang, Weiwei, et al.
Publicado: (2011)

GPR54-Dependent Stimulation of Luteinizing Hormone Secretion by Neurokinin B in Prepubertal Rats
por: Grachev, Pasha, et al.
Publicado: (2012)

miR-206 Promotes Cancer Progression by Targeting Full-Length Neurokinin-1 Receptor in Breast Cancer
por: Zhou, Yu, et al.
Publicado: (2019)

Acute Colitis Induces Neurokinin 1 Receptor Internalization in the Rat Lumbosacral Spinal Cord
por: Zhang, Ming-Ming, et al.
Publicado: (2013)

Neurokinin-2 receptor negatively modulates substance P responses by forming complex with Neurokinin-1 receptor
por: Nguyen, Lan Phuong, et al.
Publicado: (2023)

Targeting PAR2 Overcomes Gefitinib Resistance in Non-Small-Cell Lung Cancer Cells Through Inhibition of EGFR Transactivation
por: Jiang, Yuhong, et al.
Publicado: (2021)

Neurokinin-1 Receptor Inhibition and Cough
por: Turner, Richard D., et al.
Publicado: (2021)

Neurokinin 1 Receptor Antagonists for Pruritus
por: Alam, Majid, et al.
Publicado: (2021)

Transactivation of human osteoprotegerin promoter by GATA-3
por: Kao, Shyan-Yuan, et al.
Publicado: (2015)

Transactivation of the estrogen receptor promoter by BRCA1
por: Archey, William B., et al.
Publicado: (2017)

Case report: Concomitant EGFR mutation and ALK rearrangement in non-small cell lung cancer
por: Hu, Haoyue, et al.
Publicado: (2023)

TRIB3-EGFR interaction promotes lung cancer progression and defines a therapeutic target
por: Yu, Jiao-jiao, et al.
Publicado: (2020)

Sonic Hedgehog modulates EGFR dependent proliferation of neural stem cells during late mouse embryogenesis through EGFR transactivation
por: Reinchisi, Gisela, et al.
Publicado: (2013)

Aprepitant inhibits the progression of esophageal squamous cancer by blocking the truncated neurokinin‑1 receptor
por: Zheng, Yang, et al.
Publicado: (2023)

TNF-α and LPA promote synergistic expression of COX-2 in human colonic myofibroblasts: role of LPA-mediated transactivation of upregulated EGFR
por: Yoo, James, et al.
Publicado: (2013)

Mapping of neurokinin-like immunoreactivity in the human brainstem
por: Coveñas, Rafael, et al.
Publicado: (2003)

The pharmacology of neurokinin receptors in addiction: prospects for therapy
por: Sandweiss, Alexander J, et al.
Publicado: (2015)

Neurokinin-1 Receptor Antagonists against Hepatoblastoma
por: Muñoz, Miguel, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_7nocvrir0scnmt9nlh8t3v6md7