Reduced calorie diet combined with NNMT inhibition establishes a distinct microbiome in DIO mice

Treatment with a nicotinamide N-methyltransferase inhibitor (NNMTi; 5-amino-1-methylquinolinium) combined with low-fat diet (LD) promoted dramatic whole-body adiposity and weight loss in diet-induced obese (DIO) mice, rapidly normalizing these measures to age-matched lean animals, while LD switch al...

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Detalles Bibliográficos
Autores principales: Dimet-Wiley, Andrea, Wu, Qinglong, Wiley, Jerrin T., Eswar, Aditya, Neelakantan, Harshini, Savidge, Tor, Watowich, Stan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8748953/
https://www.ncbi.nlm.nih.gov/pubmed/35013352
http://dx.doi.org/10.1038/s41598-021-03670-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8748953/
https://www.ncbi.nlm.nih.gov/pubmed/35013352
http://dx.doi.org/10.1038/s41598-021-03670-5

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