Development of an Orthotopic Murine Model of Rectal Cancer in Conjunction With Targeted Short-Course Radiation Therapy

PURPOSE: Orthotopic tumors more closely recapitulate human cancers than do ectopic models; however, precision targeting of such internal tumors for radiation therapy (RT) without inducing systemic toxicity remains a barrier. We developed an innovative murine orthotopic rectal tumor model where the i...

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Detalles Bibliográficos
Autores principales: Uccello, Taylor P., Kintzel, Sarah A., Mills, Bradley N., Murphy, Joseph D., Garrett-Larsen, Jesse, Battaglia, Nicholas G., Rodriguez, Carlos J., Drage, Michael G., Ye, Jian, Love, Tanzy M.T., Johnston, Carl J., Repasky, Elizabeth A., Qiu, Haoming, Linehan, David C., Lord, Edith M., Gerber, Scott A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Scientific Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8749199/
https://www.ncbi.nlm.nih.gov/pubmed/35036637
http://dx.doi.org/10.1016/j.adro.2021.100867

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