Type 2 leprosy reaction presenting as a monoarthritis post multidrug therapy

Type 2 leprosy reaction, or erythema nodosum leprosum (ENL), involves a complex interaction between the host's immune system and Mycobacterium leprae. It may occur before, during, or after treatment and have a variable clinical presentation involving different body systems, such as skin, osteoa...

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Detalles Bibliográficos
Autores principales: Goulart, Isabela Maria Bernardes, Santana, Marcela Araujo de Oliveira, Costa, Willian Vargas Tenório da, Pavelka, Matthew Martin, Dornelas, Bruno de Carvalho
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8749206/
https://www.ncbi.nlm.nih.gov/pubmed/35036324
http://dx.doi.org/10.1016/j.idcr.2022.e01386
Descripción
Sumario:Type 2 leprosy reaction, or erythema nodosum leprosum (ENL), involves a complex interaction between the host's immune system and Mycobacterium leprae. It may occur before, during, or after treatment and have a variable clinical presentation involving different body systems, such as skin, osteoarticular, kidneys, and others. Thus, the differential diagnosis, depending on its clinical presentation, can be broad and challenging. The authors report a case of a severe monoarthritis during a type 2 reaction after the multidrug therapy (MDT) was discharged and the investigation of the differential diagnoses.

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