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Double-edged Sword Role of Iron-loaded Ferritin in Extracellular Vesicles

Human epidemiological and animal studies have demonstrated that excess iron is a risk for cancer. The responsible mechanisms are: 1) increased intracellular iron catalyzes the Fenton reaction to generate hydroxyl radicals, leading to mutagenic oxidative DNA lesions; 2) iron is necessary for cellular...

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Detalles Bibliográficos
Autores principales:	Toyokuni, Shinya, Kong, Yingyi, Zheng, Hao, Mi, Danyang, Katabuchi, Misako, Motooka, Yashiro, Ito, Fumiya
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Korean Society of Cancer Prevention 2021
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8749322/ https://www.ncbi.nlm.nih.gov/pubmed/35047450 http://dx.doi.org/10.15430/JCP.2021.26.4.244

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