Quantifying RNA synthesis at rate-limiting steps of transcription using nascent RNA-sequencing data

Nascent RNA-sequencing tracks transcription at nucleotide resolution. The genomic distribution of engaged transcription complexes, in turn, uncovers functional genomic regions. Here, we provide analytical steps to (1) identify transcribed regulatory elements de novo genome-wide, (2) quantify engaged...

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Detalles Bibliográficos
Autores principales: Rabenius, Adelina, Chandrakumaran, Sajitha, Sistonen, Lea, Vihervaara, Anniina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Protocol
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8749334/
https://www.ncbi.nlm.nih.gov/pubmed/35036951
http://dx.doi.org/10.1016/j.xpro.2021.101036

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