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Application of Deep Learning in Lung Cancer Imaging Diagnosis

Lung cancer is one of the malignant tumors with the highest fatality rate and nearest to our lives. It poses a great threat to human health and it mainly occurs in smokers. In our country, with the acceleration of industrialization, environmental pollution, and population aging, the cancer burden of...

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Autores principales: Jiang, Wenfa, Zeng, Ganhua, Wang, Shuo, Wu, Xiaofeng, Xu, Chenyang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8749371/
https://www.ncbi.nlm.nih.gov/pubmed/35028122
http://dx.doi.org/10.1155/2022/6107940
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author Jiang, Wenfa
Zeng, Ganhua
Wang, Shuo
Wu, Xiaofeng
Xu, Chenyang
author_facet Jiang, Wenfa
Zeng, Ganhua
Wang, Shuo
Wu, Xiaofeng
Xu, Chenyang
author_sort Jiang, Wenfa
collection PubMed
description Lung cancer is one of the malignant tumors with the highest fatality rate and nearest to our lives. It poses a great threat to human health and it mainly occurs in smokers. In our country, with the acceleration of industrialization, environmental pollution, and population aging, the cancer burden of lung cancer is increasing day by day. In the diagnosis of lung cancer, Computed Tomography (CT) images are a fairly common visualization tool. CT images visualize all tissues based on the absorption of X-rays. The diseased parts of the lung are collectively referred to as pulmonary nodules, the shape of nodules is different, and the risk of cancer will vary with the shape of nodules. Computer-aided diagnosis (CAD) is a very suitable method to solve this problem because the computer vision model can quickly scan every part of the CT image of the same quality for analysis and will not be affected by fatigue and emotion. The latest advances in deep learning enable computer vision models to help doctors diagnose various diseases, and in some cases, models have shown greater competitiveness than doctors. Based on the opportunity of technological development, the application of computer vision in medical imaging diagnosis of diseases has important research significance and value. In this paper, we have used a deep learning-based model on CT images of lung cancer and verified its effectiveness in the timely and accurate prediction of lungs disease. The proposed model has three parts: (i) detection of lung nodules, (ii) False Positive Reduction of the detected nodules to filter out “false nodules,” and (iii) classification of benign and malignant lung nodules. Furthermore, different network structures and loss functions were designed and realized at different stages. Additionally, to fine-tune the proposed deep learning-based mode and improve its accuracy in the detection Lung Nodule Detection, Noudule-Net, which is a detection network structure that combines U-Net and RPN, is proposed. Experimental observations have verified that the proposed scheme has exceptionally improved the expected accuracy and precision ratio of the underlined disease.
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spelling pubmed-87493712022-01-12 Application of Deep Learning in Lung Cancer Imaging Diagnosis Jiang, Wenfa Zeng, Ganhua Wang, Shuo Wu, Xiaofeng Xu, Chenyang J Healthc Eng Research Article Lung cancer is one of the malignant tumors with the highest fatality rate and nearest to our lives. It poses a great threat to human health and it mainly occurs in smokers. In our country, with the acceleration of industrialization, environmental pollution, and population aging, the cancer burden of lung cancer is increasing day by day. In the diagnosis of lung cancer, Computed Tomography (CT) images are a fairly common visualization tool. CT images visualize all tissues based on the absorption of X-rays. The diseased parts of the lung are collectively referred to as pulmonary nodules, the shape of nodules is different, and the risk of cancer will vary with the shape of nodules. Computer-aided diagnosis (CAD) is a very suitable method to solve this problem because the computer vision model can quickly scan every part of the CT image of the same quality for analysis and will not be affected by fatigue and emotion. The latest advances in deep learning enable computer vision models to help doctors diagnose various diseases, and in some cases, models have shown greater competitiveness than doctors. Based on the opportunity of technological development, the application of computer vision in medical imaging diagnosis of diseases has important research significance and value. In this paper, we have used a deep learning-based model on CT images of lung cancer and verified its effectiveness in the timely and accurate prediction of lungs disease. The proposed model has three parts: (i) detection of lung nodules, (ii) False Positive Reduction of the detected nodules to filter out “false nodules,” and (iii) classification of benign and malignant lung nodules. Furthermore, different network structures and loss functions were designed and realized at different stages. Additionally, to fine-tune the proposed deep learning-based mode and improve its accuracy in the detection Lung Nodule Detection, Noudule-Net, which is a detection network structure that combines U-Net and RPN, is proposed. Experimental observations have verified that the proposed scheme has exceptionally improved the expected accuracy and precision ratio of the underlined disease. Hindawi 2022-01-03 /pmc/articles/PMC8749371/ /pubmed/35028122 http://dx.doi.org/10.1155/2022/6107940 Text en Copyright © 2022 Wenfa Jiang et al. https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Jiang, Wenfa
Zeng, Ganhua
Wang, Shuo
Wu, Xiaofeng
Xu, Chenyang
Application of Deep Learning in Lung Cancer Imaging Diagnosis
title Application of Deep Learning in Lung Cancer Imaging Diagnosis
title_full Application of Deep Learning in Lung Cancer Imaging Diagnosis
title_fullStr Application of Deep Learning in Lung Cancer Imaging Diagnosis
title_full_unstemmed Application of Deep Learning in Lung Cancer Imaging Diagnosis
title_short Application of Deep Learning in Lung Cancer Imaging Diagnosis
title_sort application of deep learning in lung cancer imaging diagnosis
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8749371/
https://www.ncbi.nlm.nih.gov/pubmed/35028122
http://dx.doi.org/10.1155/2022/6107940
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