Complement Receptor 3 Mediates HIV-1 Transcytosis across an Intact Cervical Epithelial Cell Barrier: New Insight into HIV Transmission in Women

Transmission of HIV across the mucosal surface of the female reproductive tract to engage subepithelial CD4-positive T cells is not fully understood. Cervical epithelial cells express complement receptor 3 (CR3) (integrin α(M)β(2) or CD11b/CD18). In women, the bacterium Neisseria gonorrhoeae uses CR...

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Detalles Bibliográficos
Autores principales: Day, Christopher J., Hardison, Rachael L., Spillings, Belinda L., Poole, Jessica, Jurcisek, Joseph A., Mak, Johnson, Jennings, Michael P., Edwards, Jennifer L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8749410/
https://www.ncbi.nlm.nih.gov/pubmed/35012346
http://dx.doi.org/10.1128/mbio.02177-21

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8749410/
https://www.ncbi.nlm.nih.gov/pubmed/35012346
http://dx.doi.org/10.1128/mbio.02177-21

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