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Cleavage-Polyadenylation Factor Cft1 and SPX Domain Proteins Are Agents of Inositol Pyrophosphate Toxicosis in Fission Yeast

Inositol pyrophosphate (IPP) dynamics govern expression of the fission yeast phosphate homeostasis regulon via their effects on lncRNA-mediated transcription interference. The growth defects (ranging from sickness to lethality) elicited by fission yeast mutations that inactivate IPP pyrophosphatase...

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Detalles Bibliográficos
Autores principales: Schwer, Beate, Garg, Angad, Sanchez, Ana M., Bernstein, Mindy A., Benjamin, Bradley, Shuman, Stewart
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8749416/
https://www.ncbi.nlm.nih.gov/pubmed/35012333
http://dx.doi.org/10.1128/mbio.03476-21